There are multiple definitions - click on the translation that matches your context.

使疏远

动词

full

alienate

verb

Definitions of alienate

English

to transfer property or a right to another

The land holder was forced to alienate property in order to maintain his business.

English

to make someone feel that they are not wanted or that they do not belong to a group or in a place

The policy risks alienating female students.

English

to do something that makes someone dislike you or not want to support or help you

He has managed to alienate many senior members of his own party.